Skip to content

Chemotherapy

Cancer treatment using medicines that destroy cancer cells or slow their growth, based on the type and stage of cancer

What is chemotherapy?

Chemotherapy uses drugs that damage cells while they are dividing. Cancer cells divide faster than most normal cells and take the brunt of it, but healthy tissues that also turn over quickly are affected too: the bone marrow, the lining of the mouth and gut, and the hair roots. That is where the side effects come from.

It is used in several different situations. Before surgery to shrink a tumour, after surgery to deal with cells that may have escaped, alongside radiotherapy to make it work better, and on its own when a cancer has spread. Your oncologist chooses the drugs and the number of cycles from the cancer type, what the biopsy showed and your general health.

What it involves

Most regimens are given into a vein in a Day Care unit. A cannula is placed, or blood is drawn from a port or a PICC line if you have one, and medication to prevent sickness goes in first. The drugs themselves run over anything from thirty minutes to several hours.

Your blood counts are checked before every cycle and a session is postponed if they are too low. Some drugs are tablets taken at home instead. You are awake throughout, you can eat normally, and you go home the same day.

Recovery

The pattern repeats: the few days after a cycle are the hardest, then you pick up before the next one. Sickness is well controlled with modern anti-sickness drugs. Fatigue, taste changes, mouth ulcers and hair thinning or loss are common, and hair grows back once treatment ends.

Your blood counts dip about seven to fourteen days after each cycle, and that is the window when infection is dangerous. A temperature of 38 degrees or above, shivering, or feeling suddenly unwell during that window is an emergency: go to hospital the same day and tell them you are on chemotherapy.

Questions about chemotherapy

Will I lose my hair?

It depends on the drugs. Anthracyclines and taxanes usually cause complete hair loss, starting two to three weeks after the first cycle; several other regimens cause thinning only, and some cause none at all. Ask your oncologist which group your regimen falls into so you can plan. Hair grows back once treatment finishes, often with a change in texture or curl for the first year.

Can I keep working during chemotherapy?

Many people do, often with lighter duties or a few days off around each cycle. The days straight after a cycle are usually the hardest, and the middle of the cycle is when your blood counts are lowest and a crowded workplace carries more infection risk. Talk to your employer about flexibility before you start, and expect fatigue to build over the course of treatment.

What temperature means I should go to hospital?

38 degrees or above, or feeling shivery and unwell even without a high reading, means going to hospital the same day and telling them you are on chemotherapy. Low white cells make an ordinary infection dangerous within hours, and antibiotics need to start quickly. Do not wait until morning, and do not take paracetamol first, since it hides the fever.

Other medical oncology treatments

Treatment that helps the immune system recognise and fight certain cancers

Day Care

Supportive care focused on symptom relief, comfort and quality of life alongside cancer treatment or when disease control is no longer the main goal

Inpatient

Talk to a care coordinator about chemotherapy

Leave a number and a care coordinator calls you back with what the treatment involves and which hospital it would be at. They book a consult only if you want one

Talk to a care coordinator