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Deep Vein Thrombosis

Diagnosis and treatment of blood clots in deep veins, with management based on location and risk

What is deep vein thrombosis?

A deep vein thrombosis is a blood clot that forms in one of the large veins running deep inside the calf, thigh or pelvis. The clot blocks the vein, so blood backs up behind it and the leg swells, aches and feels tight and warm. It is usually one leg, and the swelling comes on over hours or days.

Clots form when blood sits still, when the vein wall is injured, or when the blood itself is stickier than usual. Long flights and long stretches in bed, recent surgery on a hip or knee, a plaster cast, pregnancy and the weeks after delivery, the contraceptive pill, cancer and an inherited clotting tendency all raise the risk, and often two of them stack up.

What decides the treatment is how far up the clot goes and how long it has been there. A clot confined to the calf is treated with blood thinners alone. A fresh clot filling the thigh and pelvic veins in a young person with a badly swollen leg is where your surgeon will consider removing or dissolving it, to protect the valves that clot will otherwise scar.

What you might notice

  • One calf swollen, warm and painful
  • An arm or leg swollen along its whole length
  • Leg heaviness after standing
  • Ankle swelling
  • Getting out of breath on stairs

How it is diagnosed

The examination compares the two legs. Your doctor measures the calf circumference on both sides, looks for swelling that pits under a finger, warmth, and tenderness along the line of the deep veins, and checks whether the veins just under the skin are standing out more on the swollen side.

The test that confirms it is a duplex doppler ultrasound of the leg, which shows whether the vein squashes flat under the probe. A vein full of clot will not. It also shows how high the clot reaches, and that is what changes the plan. A D-dimer blood test is often done first, and a normal result in someone at low risk makes a clot unlikely enough to look elsewhere.

If you are breathless or your chest hurts, a CT scan of the lung arteries is done at the same time, because the two are one illness. Once the clot is confirmed, expect blood tests for kidney function and clotting, and questions about family history, recent travel, surgery and cancer screening.

Recovery

Blood thinners start on the day of diagnosis and continue for three to six months, sometimes longer if the clot came without a cause or has happened before. The pain and tightness ease over one to two weeks. Walking is encouraged from the first day, since it helps the swelling more than resting does.

Most people are back at desk work within a week. A graduated compression stocking worn during the day for up to two years reduces the aching and swelling that can persist afterwards. If the clot was dissolved through a catheter you spend one to three nights in hospital while the drug runs and the scans are repeated.

What decides whether the leg stays comfortable is how much clot clears and whether the valves survive. A vein that reopens early behaves close to normal. One left scarred and blocked leaves a leg that swells and aches on standing for years, and your doctor will keep you in a stocking to manage it.

If it is left untreated

An untreated deep vein clot is dangerous, and this is one of the few leg problems where waiting is the wrong choice. Blood thinners are started the day it is confirmed.

The complication that kills is a pulmonary embolism: a piece of clot breaks off, travels to the lungs and blocks an artery there. Sudden breathlessness, chest pain that is worse when you breathe in, a racing heart, coughing blood or fainting after a swollen calf means going to an emergency department the same hour. Do not wait for a clinic appointment and do not drive yourself.

A leg that becomes tensely swollen, cold, dusky blue or purple and severely painful means the clot has blocked the leg's drainage almost completely, and the limb is at risk. That is also a same-day emergency. Over the longer term, a clot left alone scars the valves and leaves a heavy, swollen, aching leg with skin that can break down into an ulcer years later.

Questions about deep vein thrombosis

How long will I have to take blood thinners?

Three months is the minimum for almost everyone, and what happens after that depends on why the clot formed. If it followed a clear temporary cause such as surgery, a plaster cast or a long flight, three months is usually the whole course. If the clot came out of nowhere, if you have had one before, or if there is an ongoing reason such as cancer or an inherited clotting tendency, your doctor will discuss continuing for longer or indefinitely, weighing the chance of another clot against the bleeding risk of the drug. A repeat scan and a D-dimer blood test after stopping help make that call. Never stop the drug on your own, and tell any dentist or surgeon you are on it before a procedure.

Is it safe to walk and travel with a DVT?

Walking is encouraged from the first day, once treatment has started. Movement helps the swelling and the pain settle faster than bed rest, and it does not make a clot more likely to break off. Wear the compression stocking during the day if one has been prescribed. Air travel is different in the first two to four weeks, because sitting still for hours is what raised your risk in the first place; ask your doctor before booking anything long-haul, and if you do fly, take the aisle seat, drink water, and get up every hour. For the rest of the treatment period, ordinary activity, work and exercise are fine, with contact sports the usual exception while you are on a blood thinner.

Why is my leg still swollen months later?

Around one person in three is left with some swelling, aching and heaviness after a large clot, and doctors call it post-thrombotic syndrome. It happens because the clot scars the one-way valves inside the vein as it clears, so blood falls back down the leg with every step and the pressure at the ankle stays high. It is more common after a clot that filled the thigh and pelvis, after a second clot in the same leg, and in people who did not wear compression. Daily graduated compression is the main treatment and does genuinely reduce the symptoms. If the swelling is severe, or the skin over the ankle is discolouring, ask for a doppler scan, since a blocked pelvic vein can sometimes be reopened and stented.

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