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Kidney Transplant

A specialised surgeon operates to place a healthy donor kidney, while the nephrologist manages your medical care before and after the procedure

What is kidney transplant?

A transplant places a single healthy kidney from a donor into your body. The donor is either a living person, usually a close relative or spouse, or somebody who has died and whose family has consented to donation. In India both routes are governed by law, and living donation requires approval from an authorisation committee before anything is scheduled.

The new kidney goes into the lower abdomen, low on one side, above the groin. It is not put where your own kidneys sit. That position keeps the vessels short, sits the kidney close to the bladder and just under the skin where it can be felt and scanned easily. Your own kidneys are almost always left where they are.

One kidney is enough. A transplanted kidney typically begins producing urine on the table or within a day or two.

The operation is the shorter part of this. What follows it is a lifelong course of medicines that hold your immune system back from attacking the new kidney, taken every day without a missed dose, along with regular clinic visits and blood tests.

What it involves

This is a major Inpatient operation under general anaesthetic, so you are fully asleep throughout. With a living donor the date is planned well in advance and both operations run in adjacent theatres.

Your surgeon makes a curved cut in the lower abdomen on one side, about fifteen to twenty centimetres long, and works outside the abdominal cavity itself. The artery and vein of the new kidney are stitched to the vessels supplying your leg, the clamps come off and the kidney takes up blood, and the ureter is then joined to your bladder over a fine internal tube called a stent, which is removed a few weeks later in a short procedure.

The operation takes three to four hours. A urinary catheter and usually a drain are in place when you wake.

You go to a protected room or a transplant unit. The catheter stays for around five days, the drain a little less, and the anti-rejection medicines begin immediately, with blood tests every day and a scan of the kidney in the first twenty-four hours. Expect five to ten days in hospital.

Recovery

The first three months are intensive. Clinic visits and blood tests are twice or three times a week at first, weekly by a month, and monthly by three months, and this schedule is not optional: rejection is detected on blood tests before you would feel anything.

The wound is sore for two to three weeks. Most people are walking the day after surgery, off strong painkillers within a week, and doing light activity at home by three weeks. Avoid lifting anything heavy and avoid driving for six weeks, and expect to feel genuinely tired for two to three months. Return to desk work is usually at two to three months and to physical work later.

Drink the volume of fluid you are told to, weigh yourself daily, record your urine output and your blood pressure, and bring the record to clinic.

The medicines are the rest of your life. Take them at the same times each day, never stop or change a dose on your own, keep a supply ahead, and check with the transplant team before taking any new medicine, including anything bought over the counter or any traditional preparation.

Questions about kidney transplant

How long will the new kidney last?

A transplanted kidney has a finite working life. Kidneys from living donors commonly last around fifteen years and many last considerably longer, while those from deceased donors average somewhat less, and individual results vary widely in both directions. What shortens a graft most reliably is missed medication, so taking the anti-rejection tablets at the same times every day is the single largest factor in your hands. Controlling blood pressure, avoiding smoking and attending every clinic appointment all add years. If the graft does eventually fail, a second transplant is possible for many people.

What happens to my own kidneys?

They stay where they are in almost every case. The new kidney is placed low in the abdomen on one side, where the vessels are short and easy to reach, so your own kidneys are simply left alone, and most people end up with three. Removing them is a larger operation and is reserved for specific reasons: kidneys so enlarged by cysts that there is no room, uncontrollable blood pressure driven by them, repeated serious infection, or a suspicious growth. Your surgeon will tell you well in advance if removal is planned, since it is usually done as a separate operation.

What are the medicines like to live with?

You will take a combination of anti-rejection tablets every day for as long as the kidney works, at fixed times, alongside medicines to prevent infection for the first months. Doses are high at the start and are reduced over the first year, guided by blood levels. Common effects are tremor, raised blood pressure, higher blood sugar, gum changes, and a greater tendency to infections and to skin cancer, so sun protection and regular skin checks become part of life. Never start any new medicine, including over-the-counter painkillers and traditional preparations, without checking with the transplant team.

Other nephrology treatments

Monitoring and treatment of kidney damage related to diabetes

Day Care

Management of kidney disease associated with long-standing high blood pressure

Day Care

Talk to a care coordinator about kidney transplant

Leave a number and a care coordinator calls you back with what the treatment involves and which hospital it would be at. They book a consult only if you want one

Talk to a care coordinator