Skip to content

Molar Pregnancy Treatment

Treatment and follow-up for an abnormal pregnancy involving unusual growth of placental tissue

What is molar pregnancy treatment?

In a molar pregnancy the tissue that should have formed the placenta grows abnormally, and a normal baby does not develop. It arises from a fault at the moment of fertilisation. In a complete mole the egg contributes no genetic material and no foetus forms at all. In a partial mole the egg is fertilised by two sperm, so there is too much genetic material, and any foetal tissue present cannot survive.

Nothing you did caused it and nothing you could have done would have prevented it. It is slightly commoner at the two ends of reproductive life, under about twenty and over about forty, and it is reported more often in Asia than in Europe. Having had one raises the chance of another modestly, and most women who have had a molar pregnancy go on to have a normal pregnancy afterwards.

Molar tissue produces large amounts of the pregnancy hormone hCG, far more than a normal pregnancy of the same dates. That hormone is the thread running through everything: it is what raises the suspicion, it is what the treatment is checked against, and it is what the follow-up measures month after month.

What you might notice

  • Bleeding and cramping in early pregnancy
  • A missed period and a positive pregnancy test

How it is diagnosed

It is usually picked up on an ultrasound arranged for bleeding in early pregnancy, or at a routine early scan. The uterus is often larger than the dates predict, and the scan shows a characteristic appearance of the tissue where a developing pregnancy should be. A blood hCG far above what the dates would give supports it.

Your doctor also examines you for the effects of that high hormone level, which can include severe and persistent vomiting, an overactive thyroid, and raised blood pressure appearing earlier in pregnancy than it ever normally would. A blood count and your blood group are checked, because Anti-D is given to women who are Rhesus negative, and a chest X-ray is sometimes taken as a baseline.

The diagnosis is confirmed only once the tissue has been removed from the uterus and examined under a microscope. That examination also says whether the mole is complete or partial, and the answer changes how long and how closely you are followed afterwards.

Recovery

Emptying the uterus is a Day Care procedure and the physical recovery from it is short: cramping for a day or two, bleeding that settles over one to two weeks, and most women back to ordinary activity within a few days. Your next period usually arrives in four to eight weeks.

The follow-up is the long part, and it is the treatment as much as anything done on the day. Your hCG is measured at set intervals, close together at first and then monthly, until it has been normal for a defined stretch of time. For most women that means blood tests continuing for about six months from the point the level first becomes normal, and your doctor will give you the schedule in writing.

You will be advised to use reliable contraception for the whole of the follow-up. A new pregnancy raises hCG on its own, and that makes the single measurement everything depends on impossible to interpret. Emotionally this is a pregnancy loss with an unusually long tail, and asking for support through it is reasonable at any point.

If it is left untreated

A molar pregnancy cannot continue to a live birth, and it is not something to wait out. Left alone it causes heavy bleeding as the abnormal tissue outgrows its own blood supply, and it can produce enough hormone to cause dehydration from vomiting, an overactive thyroid and dangerously raised blood pressure.

The reason for the long follow-up is what happens in a minority of women: molar tissue persists after the uterus has been emptied, invades the wall of the uterus, or, less often, spreads elsewhere, most commonly to the lungs. This is called gestational trophoblastic neoplasia. It is detected by a hCG level that stops falling, flattens out or begins to rise, and it responds well to treatment when it is picked up that way. Missing the blood tests is what turns a treatable finding into a late one, so keep them even when you feel completely well.

Go the same day for heavy bleeding, for breathlessness or coughing up blood, or for a severe headache, at any point during or after the follow-up.

Questions about molar pregnancy treatment

Did I do something to cause this?

No. A molar pregnancy is caused by an error at the moment of fertilisation, in the combining of genetic material, and nothing you ate, did, took or felt before or during the pregnancy had any part in it. It is not caused by stress, by travel, by exercise, by sex or by any previous contraception. It is slightly commoner at the two ends of reproductive life and is reported more often in Asia than in Europe, and beyond that nobody can identify a reason in an individual case. It is worth saying this to yourself more than once, because the assumption that something must have caused it is extremely common and completely unfounded.

When can I try for another baby?

After the follow-up is complete, and your doctor will give you the date. The hormone level is the only way of knowing whether any molar tissue has persisted, and a new pregnancy raises that same hormone, so conceiving during the follow-up makes the test uninterpretable and can hide something that needs treating. For most women the follow-up runs about six months from the point the level first becomes normal, and longer if treatment was needed. Use a reliable method of contraception throughout. The outlook afterwards is reassuring: most women who have had a molar pregnancy go on to have a normal pregnancy, and your next one will be scanned early to confirm all is well.

Why do I need blood tests for months when I feel fine?

Because feeling fine is not evidence that the tissue has gone. In a minority of women molar tissue persists in the wall of the uterus after it has been emptied, or spreads elsewhere, and in the early stages that causes no symptoms whatsoever. The hormone level is what reveals it: instead of falling steadily to normal, the figure plateaus or begins to rise. Found that way it responds well to treatment, and found late it is a much bigger problem. The tests are quick, they are spaced out as the months pass, and they are the whole reason the outlook after a molar pregnancy is as good as it is. Keep every one of them.

Other obstetrics & gynaecology treatments

Delivery of a baby through surgery when vaginal delivery is not advisable or safe

Inpatient

Management of non-cancerous growths in the uterus, based on symptoms, size, location and reproductive plans

Day Care

Talk to a care coordinator about molar pregnancy treatment

Leave a number and a care coordinator calls you back with what the treatment involves and which hospital it would be at. They book a consult only if you want one

Talk to a care coordinator