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Vitamin Deficiencies

Assessment and correction of clinically significant vitamin deficiencies

What is vitamin deficiencies?

Vitamin D is made in the skin from sunlight and is needed to absorb calcium. Deficiency is common in people who spend their days indoors, who cover up, or who have darker skin, and it shows as aching bones, weak thigh muscles and difficulty rising from a chair.

Vitamin B12 comes only from animal foods and needs a healthy stomach lining to be absorbed. It runs low in long-standing vegetarians, in older people, after stomach surgery and in anyone on long-term metformin or acid-suppressing tablets. Its shortage affects the nerves and the blood.

What you might notice

  • Aching bones and muscles with no injury to explain it
  • Pins and needles in the hands and feet
  • Muscle cramps and weakness that keep coming back

How it is diagnosed

Your doctor asks about diet, sun exposure, gut surgery and the medicines you take, because those answers usually identify which vitamin is likely before any blood is drawn.

The examination looks for bone tenderness and weakness of the hip muscles in suspected vitamin D deficiency, and for loss of vibration and position sense in the feet where B12 is suspected. Levels are then measured, along with calcium and a blood count.

Recovery

Vitamin D is given as a weekly loading dose for six to eight weeks, and the aches usually ease in the second month. A maintenance dose follows, since the level falls again once loading stops.

B12 given by injection corrects the blood picture within weeks. Nerve symptoms recover more slowly and may not recover completely if they have been present for a long time, which is the reason for not delaying treatment.

If it is left untreated

Long-standing vitamin D deficiency softens bone, causes muscle weakness and raises the risk of fractures, and in severe cases it lowers the calcium enough to cause cramps and tingling.

Untreated B12 deficiency damages the spinal cord. It begins as tingling in the feet and can progress to unsteadiness and weakness that does not fully reverse once it is treated. The blood changes can also be masked by folate, which is why both are measured together.

Questions about vitamin deficiencies

Do I need a vitamin D test, or should I just take a supplement?

A maintenance dose is safe without testing. Testing matters where there are symptoms, since a genuinely low level needs a loading course that is far higher than a supplement, and the level is rechecked afterwards.

Are B12 injections better than tablets?

Injections are needed where the gut cannot absorb B12, after stomach surgery or in pernicious anaemia. Where absorption is intact, high-dose tablets work as well.

How long do I stay on it?

That depends on the cause. Where it was diet or sunlight, a maintenance dose and a recheck. Where absorption is the problem, replacement is usually lifelong.

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